Search on: ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G, MEMBER 2 
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Descriptor English:   ATP Binding Cassette Transporter, Sub-Family G, Member 2 
Descriptor Spanish:   Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2 
Descriptor Portuguese:   Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP 
Synonyms English:   ABCG2 Protein
ABCG2 Transporter
CD338 Antigen
Antigen, CD338  
Tree Number:   D12.776.157.530.100.228.500
D12.776.395.550.020.457.500
D12.776.543.550.192.457.500
D12.776.543.585.100.228.500
D23.050.301.264.035.272
D23.101.100.110.272
Definition English:   An ATP binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56579 
Unique Identifier:   D000070997 

Occurrence in VHL:
 

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